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Cutline Summer, for your next chapter at Otago

CELS191 Summer prep course.

Prepare for Otago HSFY with cell biology, genetics and microbiology. Cutline Summer connects how a cell works with DNA, inheritance and infection, with guided explanations and practice.

Included in the whole Cutline Summer programme.

Get the free HSFY plan and guide

Free. No card. One tap in the email to confirm. If you do not confirm, we keep your address for up to 7 days to send two reminders, then delete it.

Get the free parent guide
Lesson previewFrom the Summer beta

How a cell membrane works

Water meets the membrane on both sides. Look at which parts of each phospholipid face the water, and which parts face one another.

A cell membrane has two layers of phospholipids. Their water-facing heads point outward, while their nonpolar tails face inward, away from water.View full-size diagram

A closer look at the phospholipid bilayer. Simplified diagram, not to scale.

Image credit

Illustration by Mariana Ruiz (LadyofHats), labels removed by Masur.

Wikimedia Commons

Public domain. Image unchanged.

Try it yourselfWhere do phospholipid tails face in a bilayer?

How to prepare for CELS191

If biology has mostly meant memorising names at school, use summer to practise explaining a process. A labelled cell is a start. Explaining how a change to its membrane affects movement of a substance is the next step.

  1. Connect structures to jobs

    Sketch a cell from memory. Beside each structure, write what it does and what would change if it stopped working. Check your school notes, then redraw the parts you missed.

  2. Separate DNA, genes and chromosomes

    Explain how these terms relate before revising inheritance. Then trace the path from DNA to RNA to protein. Keep the process and the location clear in your explanation.

  3. Explain movement across a membrane

    Practise distinguishing diffusion, osmosis and active transport. Draw the concentration gradient and state whether energy or a transport protein is involved.

Try the reasoning

An introductory Cutline example, not an official exam question.

A membrane protein that uses ATP to move a solute against its concentration gradient stops working. What happens to that transport process?

Show the explanation

Transport through that protein stops. Movement against the gradient needs the energy supplied by ATP. This does not mean all movement across the membrane stops: other channels, carriers and diffusion routes may still operate.

Name the affected mechanism, explain why it changes, and keep the claim specific to the information given.

What the CELS191 Summer course will cover

Realistic cell biology exam-style questions, showing step by step how to use the concepts to work out the answer.

Planned Cutline Summer modules. These describe our preparation scope, not an official university course outline or a claim that every assessment is covered.

  1. Module 1

    Life and its building blocks

    Living systems, natural selection, evolutionary trees, cell types, carbohydrates, proteins, lipids and nucleic acids.

    Practise applying it: Compare cell features and use them to justify a classification or evolutionary relationship.

  2. Module 2

    Membranes and cellular transport

    Membranes, diffusion, osmosis, active transport, compartments, protein trafficking, endocytosis, exocytosis and cellular recycling.

    Practise applying it: Predict how water or a solute moves when membrane conditions change.

  3. Module 3

    Cell shape and organisation

    Cytoskeleton, cell junctions, extracellular matrix, plant walls, turgor, nuclear pores, ribosomes and DNA packing.

    Practise applying it: Connect a damaged cell structure with the function most likely to be affected.

  4. Module 4

    How cells obtain energy

    ATP, cellular respiration, proton gradients, ATP synthase, photosynthetic light reactions and carbon fixation.

    Practise applying it: Trace energy transfer and predict how disrupting a proton gradient affects ATP production.

  5. Module 5

    DNA and gene expression

    DNA structure, transcription, RNA processing, the genetic code, translation, DNA replication and repair.

    Practise applying it: Read a sequence and connect a DNA change to its possible effect on a protein.

  6. Module 6

    Cell division and chromosomes

    Chromosome sets, the cell cycle, mitosis, meiosis, genetic variation, chromosome abnormalities and X-inactivation.

    Practise applying it: Track chromosomes through division and explain how an abnormal distribution could arise.

  7. Module 7

    Inheritance and population change

    Genetic crosses, probability, dominance, environmental effects, linked genes, allele frequencies, drift and selection.

    Practise applying it: Use a genetic cross or allele frequencies to calculate a stated inheritance probability.

  8. Module 8

    Genomes and human health

    Reference genomes, genetic variation, comparative genomics, ancient DNA, mutation effects, pedigrees and disease risk.

    Practise applying it: Use a pedigree and variant evidence to evaluate an explanation for inherited disease.

  9. Module 9

    Studying and changing gene function

    Gene experiments, transgenesis, gene editing, gene therapy, cell differentiation, stem cells, PCR and genetic tests.

    Practise applying it: Choose a genetic method and explain what its result can establish.

  10. Module 10

    Bacteria and microbial communities

    Bacterial structure, Gram staining, survival, growth, metabolism, microbial communities, research methods and the microbiome.

    Practise applying it: Interpret a growth curve and use cell features to distinguish bacterial groups.

  11. Module 11

    Viruses, infection and evolution

    Viruses, replication, bacterial gene transfer, phages, infection, toxins, antibiotic targets, resistance and pathogen evolution.

    Practise applying it: Explain why an antibiotic targets a bacterium and how resistance can spread.

Part of Cutline Summer.

One programme covering CELS191, CHEM191, PHSI191 and HUBS191. Choose Cutline Summer for the summer, or Summer + Cutline HSFY 2027 to carry on through every HSFY paper in 2027. The Summer Mentor Circle (Nov to Feb only) is by offer from the application.

Short lessons, tutor walkthroughs and exam-style practice are planned for Summer. Try a beta lesson to see the approach while the full programme is being built.

Summer Mentor Circle, 50 places

Summer + Cutline HSFY 2027 + Summer Mentor Circle

NZ$1,949or $650 + $650 + $649

Chosen on suitability from the application.

HSFY Head Start Accelerator

Cutline Summer

NZ$699or 3 x $233

Programme access 16 November 2026 to 28 February 2027.

Prices are in NZD and include GST. These are whole-programme plans, not separate paper purchases. Full refund within 14 days of paying, and the first module guarantee to 31 December 2026.

Questions about CELS191 preparation

Should I learn all of CELS191 before university?

You do not need to turn summer into a full semester. Our suggested starting point is cells, membranes and the relationship between DNA and proteins. Use those foundations to follow unfamiliar examples, then explore the wider Summer modules if you want more structure.

Is this different from the CELS191 question bank?

Yes. Summer is preparation before the year begins. If you are already taking the paper, visit CELS191 practice questions for the in-year practice options.

For official paper information, see Otago’s CELS191 page and its HSFY preparation guidance.

Explore the other Summer papers

Read the HSFY summer preparation guide

Take the free plan and guide with you

A plan around your own exams and summer, plus the guide. Both free.

Get the free HSFY plan and guide

Free. No card. One tap in the email to confirm. If you do not confirm, we keep your address for up to 7 days to send two reminders, then delete it.

CELS191 summer prep course | Cutline